Monday, 13th February 2012


MAC13243 the next big antibacterial compound?

Posted on 29. Sep, 2009 by admin in Health

MAC13243 the next big antibacterial compound?

MAC13243 could be the next big thing in the treatment of antibiotic resistant bacterial infections. A new bacteria-killing agent, MAC13243, but it’s nothing to do with the current antibiotics or likes!

According to Canadian researchers they found a new chemical that could actually target drug-immune bacteria in an action different from that of an antibiotic. They christened it as MAC13243.

According to scientists of the McMaster University their discovery could well be a breakthrough leading to development of several new path-breaking interventions int he control of stubborn, incurable, and antibiotic-resistant bacterial infections.

It should be noted here that there have been only 2 classes of new antibiotics developed in the last 4 decades.

The compound could lead to new options to treat antibiotic-immune bacterial infections, believes Eric Brown et al., of Michael DeGroote Institute for Infectious Disease Research.

While the existent generation of antibiotics kills bacteria by preventing cell wall, DNA and/or protein synthesis, the new compound discovered by the McMaster University team of researchers, the MAC13243 blocks one step in development of bacterium’s cell surface; which was hitherto not focused as antibiotic or bacterial physiology.

You can read more about MAC13243 and the McMaster University teams findings in the Nature Chemical Biology journal.

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